It's a matter of setting up this data properly. In this example I'll be setting up two users, one for the http://www.mysite.com/joe and the other for http://www.mysite.com/bill. I'll assume the document root for mysite.com is /public_html.
| joe | bill | |
| Full Web Site URL: | http://www.mysite.com/ | http://www.mysite.com/ |
| Web Site Directory | /public_html | /public_html |
| Starting Directory | /public_html/joe | /public_html/bill |

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